The Stromal Vascular Fraction (SVF) is a cell population that can be isolated from adipose tissue. In SVF, you can find stem cells, pericytes, endothelial cells (i.e., those that cover the inner surface of blood vessels), adipocytes, fibroblasts, and cells of the immune system.
The stem cells of the stromal-vascular fraction, which have long had a prominent role in the field of regenerative medicine, are undifferentiated multipotent adult cells (mesenchymal stem cells - MSC), which can differentiate into different cell types and thus rebuild numerous damaged tissues. These cells have similar properties to the stem cells extracted from the bone marrow, the extraction of which requires, however, invasive and difficult procedures for the patient.
The preservation of stromal vascular fraction (SVF) offers a unique source of stem cells that is affordable and very easy to extract.
With a small amount of adipose tissue, it is possible to isolate a very good amount of cells that can be used and stored for various immediate and future medical applications.
The cells present in the SVF are increasingly being used in the field of aesthetic medicine because they represent a therapeutic strategy for skin rejuvenation, scar repair, elimination of wrinkles and of stretch marks. These are just a few of the effective treatments that an increasing number of men and women are using from their adipose tissue-derived stem cells to improve their appearance.
The future of the SVF cells is certainly in regenerative medicine and the applications in this field are numerous and include, for example, treatments for the regeneration of damaged tissues, such as ulcers caused by diabetes or radiotherapy. Mesenchymal stem cells, the most abundant population present in the SVF, are being used in clinical trials for the reconstruction of cartilage, bones and tendons, which will be used in the immediate future for sports injuries and post-traumatic and post-surgical injuries.